Good evening my paper is a comparative study on the effect of dajjal amide versus timolol on ocular blood flow in patients with normal tensorflow coma glaucoma is a condition characterized by progressive retinal ganglion cell death and associated we shall feel loss elevated intraocular pressure is not the only risk factor other causes like ischemia to the optic
Nerve and dysfunctional vascular regulation can also cause a progression in glaucoma in normal tension glaucoma the iop independent factors predominate for the progression of glaucoma moving this is it a typical picture picture of an optic nerve with in superior rim loss with a corresponding field effect in 2007 the world glaucoma consensus have reported that
A lower ocular perfusion pressure a lower ocular blood flow and a vascular dysregulation can cause progression in glaucoma and ever since then there are lot of little literature evidence which says that the retrobulbar vasculature is an important open parameter in the progression of glaucoma and assessment of retrobulbar parameters can be assisted by the color
Doppler imaging and our recent evidences from literature says it can be linked with glaucoma progression and visual field loss it has been hypothesized that dars olamide increases ocular blood flow and it can be studied by a color doppler imaging color doppler imaging can be studied by ge so no ct ultrasound system with a 7.5 mega watts linear probe and color
The in color doppler imaging we measure the velocity the velocity zinka of thermic artery central retinal artery and short posterior axillary artery which are the main vessels which are responsible for the ischemia to the nerves so once the velocities are calculated the machine gives us the resistive index this is the machine color doppler machine and this is the
Reporting from the machine we get the peak systolic velocity and then destroy leak velocity we did a small sample to determine the normal data from our population and we found the togas an increase in resistive index with age this is the norm penomet of pattern with a peak and a trough of color doppler imaging this is a picture of her glaucoma test patient with a
Flattening of the peaking so with a basic background in mind we decided to do a study to find the effective dose olamide ante mala on ocular blood flow using color doppler imaging in normal tense of glaucoma patient it was a prospector study we included newly diagnosed mild to moderate normal tense of glaucoma patients we did a baseline glaucoma testing and a color
Doppler imaging the patients were randomized into dorsal maidan timolol group and they were given medicines for a period of 12 weeks and repeat color doppler imaging was done after 12 weeks glaucoma evaluation and ocular blood flow was analyzed post treatment also we included as i told the included mild to moderate normal tense of patients with a best corrected
Visual acuity of 20 by 40 and who were willing for follow we excluded patients with all types of other glaucoma and with other systemic disorders without with current use of steroid use during the initial visit we measured the pulse rate we calculated where the opp but with the bp and the pulse rate and we did a slit lamp evaluation go new scope evaluation fundus
Evaluation field evaluation intraocular pressure was measured and we did a color doppler imaging as a baseline and then the patient were the once the patient was diagnosed abnormal tension glaucoma the patients were taken the color doppler imaging and the every alternate patient where it was given timolol final measurement was taken after to analyse so basically
The study patients were divided into two groups timolol group and/or zalem a group the baseline cda measurements were taken and cda were taken after treatment so we had 11 patients in each group and the leap in our study we did not find any significant decrease in the resistive index in the dolomites group and dog timolol group in ophthalmic artery and central
Retinal artery however in short posterior axillary artery we found that there was a significant reduction in resistive index in the dorsal amide group um coming onto the vascularization of the outter a tonight is mainly by the posterior axillary artery and posterior axillary artery plays a very important role in the progression of glaucoma ischemia to the pca
Causes progression of glaucoma and analysis or analysis of the velocity of posterior axillary artery can give a clue for the progression of glaucoma it’s a but it requires a little skill for as the vessel is little small compared to of tannic artery and central retinal artery literature says that a decrease in ocular perfusion pressure and an increase in resistive
Index can cause progression in glaucoma and color doppler imaging can be one of the prognost prognosticate of marker and case erectile have reported that normal tension glaucoma is mainly determined by the retrobulbar hemodynamics 72% of the literature says that dajjal amide increases ocular blood flow by extra cellular residue cysts and selective inhibition of
Ci inhibitor a word however our data did not show a significant reduction in resistive index in the ophthalmic artery and central retinal artery but it showed a significant reduction in resistive index in short posterior axillary artery ranking natal also showed a similar result like our study however our short table study was a had a shot a small sample and had
A very short follow-up so to conclude perfusion of the optic nerve head is directly related to retrobulbar circulation and regnier resistive index can be a problems to get to marker in uncontrolled low coma and normal tension glaucoma thank you thank you
Transcribed from video
AIOC2020 Semi Finals DR PRATHEEBA DEVI NIVEAN Glaucoma "FP88 COMPARATIVE STUDY ON EFFECTS DORZOLA By aioseditorproceedings