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Now let me discuss about the class 5 agents so if you take the classify agents the examples they include digoxin they include adenosine right they include adenosine the other drugs are magnesium and then we have atropine and the other drugs are even your potassium right even your potassium now let me discuss one by one you take the drug that is digoxin right
You take the drug that is digoxin remember digoxin it increases the vehicle activity right now because it increases the vehicle activity so digoxin it increases the vehicle activity so remember because digoxin increases the vehicle activity it is used for controlling the ventricular rate in atrial fibrillation right in atrial fibrillation and as well as the
Atrial flutter right atrial fibrillation and atrial flutter so that is about your digoxin next you take the other important drug that is adenosine right the other important drug that is adenosine now if you see this adenosine remember adenosine it opens the potassium channels because the adenosine opens the potassium channels this adenosine it lead to the hyper
Polarization of the av node right adenosine it opens the potassium channels right now so once there is opening of the potassium channels what will happen there is hyper polarization of the av node so this lead to hyper polarization of the av node now because there is hyper polarization of the av node the av node it gets inhibited now once the av node is being
Inhibited the impulses from atria will not reach the ventricle and thereby it is used as the drug of choice for the treatment of psvt right drug of choice for paroxysmal supraventricular tachycardia now the very very important point is the adenosine it is very short acting drug right it is a very short acting agent and if you take the t half the t half is
Around 10 seconds right the t half is around 10 seconds now because the adenosine it has the t half of only 10 seconds therefore the adverse effects like flushing of the face and bronchospasm they are also short-lived right so the adverse effects like flushing of the face and as well as bronchospasm right as well as the bronchospasm they are short-lived right
They are short-lived next now you take the other drug that is now continuing this adenosine remember we have a drug called as theophilum theophilin it is an adenosine receptor antagonist remember theophylline it is an adenosine receptor antagonist because theophilin inhibits the adenosine receptor theophylline right theophylline it is adenosine right it is
Adenosine receptor antagonist right it is an adenosine receptor antagonist now because theophilin is an adenosine receptor antagonist theophylline inhibits the action of the adenosine right inhibits the action of the adenosine whereas you take the other agent the other agent is your diplydermal right the other agent is dipredamore so if you take this particular
Dipyridamole dipyridamole it potentiates the action of the theophylline by inhibiting the reuptake of adenosine okay so dipyridamole right diperitamole it potentiates the action of adenosine by inhibiting the reuptake right by inhibiting the reuptake of adenosine right by inhibiting the reuptake of adenosine right so these are important points regarding the
Adenosine now we have the important agent that is magnesium remember magnesium is used for the treatment of both congenital and acquired long qt syndrome right this is a very important multiple choice question so it is used for right it is used for congenital and acquired long qt syndrome right so that is the important point regarding the magnesium so let
Me shortly revise the classify agents the classify agents they include digoxin adenosine magnesium atropine and as well as the potassium and if you take the digoxin digoxin it increases the vagal activity and it is useful for controlling the ventricular rate in atrial fibrillation and atrial flutter and the other agent if you take adenosine adenosine opens the
Potassium channels and lead to hyperpolarization of the av node and this adenosine it is a drug of choice for the treatment of paroxysmal supraventricular tachycardia and it is a very short acting agent the t half is around 10 seconds and therefore the adverse effects like flushing of the face and bronchospasm they are also short-lived and if you take an agent
Called theophilin theophylline being adenosine receptor antagonist inhibits the action of the adenosine whereas you take dipredamol dipredamol it potentiates the action of the adenosine by inhibiting the reuptake of adenosine and if you take magnesium magnesium is used for the treatment of both congenital and as well as acquired long qt syndrome
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Anti Arrhythmic Drugs – Class 5 :- #Pharmacology – #USMLE, #NEET PG, #INI-CET, #FMGE By Dr.G Bhanu Prakash Animated Medical VideosliveBroadcastDetails{isLiveNowfalsestartTimestamp2021-07-06T134512+0000endTimestamp2021-07-06T135348+0000}