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Anti emetic drugs (easy notes) – classification, uses ,differences, adverse effects

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Welcome back to the channel everyone in this video we will discuss about the antiemetic medicine with its classification and also we will discuss about the prokinetic drugs like metoclopramide and domperidone and also the difference between these drugs of pro kinetics since i’m trying to upload my videos regularly thinking that all of you guys will support this

Channel so if you are enjoying my videos and content of this channel please consider subscribing and support me and also don’t forget to press the bell icon so that you could get the daily updates now without any further delay let’s start our intro and today’s topic hello namaste ola previous viewers welcome to my channel met gossip sd i am tsubasa the main

Objective of this channel is we bring basic medical and clinical science topics explanation with the related diagrams much as possible and frequently asked exam oriented questions of that related topic so make sure you hit that red button of subscription and the bell icon so that you could never miss the updates so antiemetic drugs let’s classify these drugs

Antiemetic drugs are classified into six different types they are number one anticholinergics number two as one antes dominick’s number three neuroleptics number four pro kinetics number five 5 st three antagonists and number six adjuvant antiemetics now let’s mention drugs the drugs in anticholinergics are hyacinth and dicyclomine the drugs in s1 and histamine ik

Are promethazine diphenhydramine doxylamine cyclize i’m miss cycles i’m and saneras i’m number three neuroleptics the drugs are chlorpromazine probe clos paris wing and haloperidol number four pro kinetics the drugs are metoclopramide dumper adone cisapride mosop ride and take a cerrado number five the drugs in 5 st three antagonists are on the set ron and granny

Citron number six the drugs in adjuvant antiemetics are dexamethasone benzodiazepine and cannabinoids now the next topic we have prokinetic drugs in prokinetic drugs we will discuss briefly about the mechanism of action uses contraindication and adverse effect of main to drugs they are metoclopramide and don’t paradorn now we can see in the screen the drugs used

In prokinetic drugs are metoclopramide don’t perry don’t see supplied mosop ride and take a sarin but i will be discussing about metoclopramide and tom period on which is the arrow arrow part it’s mechanism of action is metoclopramide acts through both dopaminergic and serotonergic receptors that is it acts through d2 antagonism 5s t4 agonism and 5s t3 antagonism

Let’s discuss number one mid moa by d2 antagonism motoko pramod or acts by dopamine acting through d2 receptor is an inhibitory transmitter in the gastrointestinal system normally it acts to delay gastric emptying motoko pramod also causes gastric dilation and esophageal spencer relaxation motoko pramod blocks d2 receptors and has opposite side effect now let’s

Discuss number two metal metoclopramide 5s d4 agonism 5s t4 receptors activation on primary afferent neuron of ens via effect a excitatory interneurons which leads to enhance acetylcholine release from my enteric motor neuron and it results as gastric whoring and le s tone effects now metoclopramide mechanism by 5’s t3 antagonism metoclopramide acts at very high

Concentration which leads to block v st 3 receptors in inhibitory magnetic interneurons and it results gastric hurring the adverse effect of these drugs are they are generally well tolerated it may leads to sedation dizziness loose stool muscle dystrophies and the long term use can cause parkinsonism galleria and gynecomastia now after the adverse effect now let’s

Move on the uses prokinetic drugs are commonly used in antiemetic as a gastro kinetic in dyspepsia and in gastroesophageal reflux disease that is ze id now let’s add the important content on this topic the defense between prokinetic drugs which is metoclopramide and domperidone so first let’s differentiate their mechanism of action metoclopramide acts as three

Receptors which is v st for organism d2 antagonism and 5s t3 antagonism whereas don’t period on acts only in d2 receptor in which is acts as it blocks d2 receptor in upper gi t which leads to increase release of acetylcholine and results in increased peristalsis increased stone of less and stomach which results as increased the gastric emptying and at last it results

Decrease vomiting now let us discuss about the efficiency of these drugs metoclopramide is more efficacious whereas dumper radon is less efficacy than meta parameter now moving towards adverse effect metoclopramide has extrapyramidal side effects motoko parameter also crosses blood-brain barrier whereas don’t pay return is less extrapyramidal side effects and also

Don’t be read on do not cross blood-brain barrier now let us discuss uses of this go drug motoko pramod cannot be used in l-dopa bromocriptine induce vomiting in parkinsonism patient whereas don’t be returned can be using l-dopa induce vomiting in parkinsonism patient now let’s discuss the last part of this topic the question/answer part the questions which may

Be asked related to this topic in exams are classify the antiemetic drugs number one number two question may be asked write down the mechanism of action adverse effect and uses of metoclopramide and number three write down the difference between metoclopramide and don’t pay a donation thank you for making me a part of it a please like the video ect subscribe to

My channel and face the prayer icons so that you could never miss the new outfits that i will be posting next video will be probably of the classification of antiprotozoal drugs and description of metronidazole till then signing off many activities bye bye

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Anti emetic drugs (easy notes) – classification, uses ,differences, adverse effects By MedgossipHD