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Bisoprolol | Wikipedia audio article

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The silver law marketed under the trade names of betta among others is a medication most commonly used for heart diseases this specifically includes high blood pressure chest pain from not enough blood flow to the heart and heart failure it is taken by mouth common side effects include headache feeling tired diarrhea and swelling in the legs more severe side effects

Include worsening asthma blocking the ability to recognize low blood sugar and worsening heart failure there are concerns that use during pregnancy may be harmful to the baby the sopra lal is in the beta blocker family of medications and is of the beta 1 selective type the sopra law was patented in 1976 and approved for medical use in 1986 it is on the world health

Organization’s list of essential medicines the most effective and safe medicines needed in a health system thus oprah lal is available as a generic medication the wholesale cost in the developing world is about 2.9 eight-to-four united states dollars in 94 cents per month in the united states as of 2015 it costs about 25 to 50 united states dollars a month medical

Uses the silver lal is beneficial in treatment for high blood pressure hypertension reduced blood flow to the heart cardiac ischemia congestive heart failure and preventive treatment before in primary treatment after heart attacks decreasing the chances of recurrence the so prolong target’s hypertension elevated blood pressure in cardiac ischemia the drug is used

To reduce the activity of the heart muscle so reduces oxygen and nutrient demand and reduced blood supply can still transport sufficient amounts of oxygen and nutrients but so prolong can be used to treat cardiovascular diseases such as hypertension coronary heart disease arrhythmias ischemic heart diseases and myocardial infarction after the acute event patients

With compensated congestive heart failure may be treated with bisoprolol as a co medication usually with an ace inhibitor a diuretic and a digitalis glyco suit if indicated in patients with congestive heart failure it reduces the need for and the consumption of oxygen of the heart muscle it is very important to start with low doses as the sopra law reduces also

The muscular power of the heart which is an undesired effect in congestive heart failure side effects overdose of bisoprolol leads to fatigue hypotension low blood sugar bronchospasms and bradycardia bronchospasms and low blood sugar because at high doses drug can be an antagonist for beta-2 adrenergic receptors located in lung and in liver bronchospasm is due

To blockage in lungs of beta 2 receptor and low blood sugar because of decreased stimulation of glycogenolysis and gluconeogenesis in the liver via beta 2 receptor cautions beta-blockers should generally be avoided in people with a history of asthma or bronchospasm as they may make the disease worse a beta 1 selective beta blocker like the soper law may be tried

In those in whom other options are not available pharmacology mechanism of action the silver lal is kardia protective because it selectively and competitively blocks catecholamine adrenaline stimulation of beta-1 adrenergic receptors adreno receptors which are mainly found in the heart muscle cells and heart conduction tissue cardio specific but also found in

Juxtaglomerular cells in the kidney normally adrenaline and noradrenaline stimulation of the beta one adreno receptor activates a signaling cascade g’s protein and camp which ultimately leads to increased contractility and increased heart rate of the heart muscle and heart pacemaker respectively the so prolog competitively blocks the activation of this cascade so

Decreases the adrenergic tone stimulation of the heart muscle and pacemaker cells decreased adrenergic tone shows less contractility of heart muscle and lowered heart rate of pacemakers beta1 selectivity the sopra law beta1 selectivity is especially important in comparison to other non-selective beta blockers the effects of the drug are limited to areas containing

Beta 1 adreno receptors which is mainly the heart and part of the kidney the sopra law minimizes the side effects that might occur from administration of a nonspecific beta blocker where blockage of the other adreno receptors fated to beta 3 alpha 1 alpha 2 occurs the other receptors elicit a variety of responses in the body and their blockage could cause a wide

Range of reactions but beta 1 adreno receptors are cardio specific for the most part making the sopra law ideal for treatment of cardiac events but sopra law has a higher degree of beta 1 selectivity compared to other beta 1 selective beta blockers such as atenolol metoprolol and botox law however nibble all is approximately 3.5 times more beta 1 selective rina

Angiotensin system the sopra lal inhibits reena and secretion by about 65% in tachycardia by about 30% pharmacokinetics the sopra lal has both lipid and water-soluble properties it has an approximate half-life of 10 to 12 hours and when ingested has high bioavailability approximately 90% when being eliminated the body evenly distributes it 50 to 50 between kidney

Excretion and liver biotransformation then excreted society and culture the sopra lal is available as a generic medication history the sopra law was patented in 1976 and approved for medical use in 1986 it was approved for medical use in the united states in 1992 references external links

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