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Breast Cancer Prevention Research Video

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Now with a segment on research studying medications for breast cancer prevention here’s our reporter laura windsor star trials is the second prevention trial for breast cancer that has been studied on a national level these trials determine the effectiveness of certain medications in preventing breast cancer dr. janet id of desert regional medical center in palm

Springs discusses the medications currently being studied star trial is the study of tamoxifen and raloxifene in other words it’s comparing two medications to see which one might be more advantageous to prevent breast cancer they notice retrospectively are looking back on a population of women who had osteoporosis and were being treated with lavar loxapine that

They had less breast cancers and that stimulated researchers to look at that as a potential drug for prevention of breast cancer the first prevention trial rp1 was published in the late 1990s and proved that tamoxifen can decrease a woman’s risk of breast cancer by as much as fifty percent these are patients who carry a high risk of getting breast cancer this star

This stimulated the study of the p2 trial the p2 trial is looking at comparing tamoxifen with another medication called raloxifene many people know it as a vista to see if one may have the one advantage over the other as far as prevention is concerned and as far as side effects are concerned the first part of the p2 study has been published and it looks like both

Are equally protective in high-risk women with breast cancer who do not have insight to breast cancer and who are postmenopausal however raloxifene definitely has sire has fewer side effects it has forty percent less uterine cancers associated with it and a 30-percent risk in reduction of deep vein thrombosis and pulmonary embolism we’re the only center in the

Coachella valley that is sponsoring the program i’m the principal investigator of the p2 trial we have accrued which means accumulated approximately 30 patient onto the trial in fact half of them are still on the trial and half of them have already completed the trial or have gone out five years so i have a whole group of patients that i follow every six months in

My office with blood tests and examinations they’re locked into very close follow-up to see what their risk how their risk is going and develop your breast cancer which ones are getting it which was have not gotten it yet both of these treatments are 45 years total hoping that it will continue to provide a protection for another five years but the medications are

Not given for more than five years many patients who are put on the p 2 trial are already very concerned or what we call cancer phobic they’re very concerned about getting breast cancer these are women who have had a very strong family history which means the first degree relative with breast cancer they’ve had for example a biopsy that has shown a high risk type

Of tissue which makes them concern that they’re going to develop breast cancer it also has to do with the patients who have not had children those who have not had children are at higher risk or those who have had children at a later age where a little higher risk this has to do with the age when women go through menopause it’s a whole series of questions that we

Asked we do a risk profile on them to see what kind of risk they have of getting breast cancer we offer the trial to those who have approximately 1.7 percent chance of getting breast cancer in the next five years that’s considered high risk those women are then interviewed and fully apprised fully informed about the risks and benefits of the trial and some go on

It some don’t hopefully we’ll have even better agents on the market that women can take by mouth to prevent them from getting breast cancer prevent the mutation from occurring that causes breast cancer research is ongoing to develop better ways to detect and treat cancers and cancer prevention is on the forefront of these studies i’m lora windsor for the american health journal you

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Breast Cancer Prevention Research Video By AHJCancer