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COVID Update || Vaccine Allergies || What is polyethylene glycol? || PEGylation Explained

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#COVID # coronavirus #vaccine #mrnavacccine #vaccineallergies

Hi guys welcome back to the channel and happy new year now ever since the mrna vaccine have become available to the public there have been a few cases of vaccine allergy reports now this week we are going to dive deep down into this topic and look at what are the components of what is causing these vaccine allergies now if you remember part of my video a couple

Weeks ago i mentioned i would come back to talk about this topic let’s have a recap now for the most part these injection reactions happen within 10 minutes after the injections and i have several speculations but i also keep an eye on the fda’s latest investigations and i’ll update you all as soon as i find out more on this topic so in fact after i attended an

Acf’s webinar webcast back in mate presented by a scientist from modern i have some concerns about one of the additives in the vaccine formulations and i would put it on my blog post it was the polyethylene geico or commonly known as peg so today let’s look at what polyethylene geico is and by the way if you’re new to the channel i’m dr han i love to produce

Science review content update on the latest global health topic i also like to share tips for students learning development if these are your anxious topic please consider subscribing to the channel if you are coming back for another week of covert 19 update thank you very much so without further ado let’s dive into the topic so today we are going to talk about what

Causes vaccine energy what is this peg compound and why is it in the vaccines like always a disclaimer this video is my interpretation and summary of properly available scientific information this video does not serve as any advice on treatment diagnosis and prevention of any diseases and if i mentioned any commercial companies in the video i have no affiliations

With them so let’s look at some of the backgrounds the cdc issued a statement on december 31st talking about covet-19 vaccine allergies and it suggests people that are allergic to the first dose should not get the second dose and they believe the possible agent that is causing the problem is a compound called polyethylene glycol or peg now today we are look at

What is peg and what does peg do and what contains peg and how common is this peg allergy first fact what is peg peg stands for polyethylene glycol it is important to not confused with ethylene glycol which is an anti-freeze okay they are not the same ethnic geico is a monomer and peg is a polymer the peg peg is a biologically compatible polymer that have been

Clinically approved to use in many injectable drugs and in fact it is also used as a stew softener such as this one now fact number two what does peg do in general now the process to add peg to any drug compound is called pigulations the number one reasons to have peg or to do this regulation process is to make drugs or vaccines last longer in the body for it to

Work it ties into a concept called pharmacokinetics now that is pretty deep science i won’t go into detail in this video the general intent is to reduce non-specific interactions with the rest of the body and also reduce the compound to interact with innate immune system the immune system that we were born with now if we interact a lot with our innate immune

System we will basically clear out the compound and make these drug compound useless in our body so peg is necessary in this case so fact number three what contains peg so phe there are different formulations the longer the polymer the larger the number such as this one peg 3350 is used in the stew softener like i said earlier mpeg 2000 is used in covet 19

Vaccines such as here i bracketed this is an ingredient list on the pfizer vaccines now pg generally have very low toxicity and it’s not really absorbed into our body that much other uses of peg include common cancer drugs household products food and even cosmetics so they are pretty much in many places although they may be in different lengths so their molecular

Weight or they’re not the same in some cases so how common is peg allergy in fact pg allergies are more common than we used to think according to a very recent case study by uk investigators at cambridge university hospitals that they concluded that the life-threatening anaphylaxis okay very serious allergic reactions are rare but possible now it also increased

With the risk when you are injecting higher molecular weight or heavier peg compound and the risk also increased with second or subsequent exposures people that are allergic to multiple medications should be cautious in some cases they are in fact allergic to the peg compound rather than the drug molecule itself so very quickly today the take-home message is that

Polyethylene glycol or peg peg is clinically approved polymer used in many consumer products food and drugs they are considered to have low toxicity and systemic absorption is minimum and pig is used in both pfizer and moderna called it 19 vaccines now life-threatening allergic reactions to pgs is rare but possible and they are documented it is very important

To follow the cdc recommendations upon having allergic reactions so to learn more here are a couple of the links the first of the links is to show you there are in fact many drugs that are approved by fvda that contained the pig relations or pegulator the second link here is the cdc covet 19 vaccine and allergic reactions report and with recommendations and

The last one is the study that i quoted out that is published by the uk investigator so i hope this video have provided some explanations on polyethylene glycol alright so that is all for this week’s covet 19 update and i’ll see you again next sunday and i wish you all have a happy wonderful and healthy new year bye you

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COVID Update || Vaccine Allergies || What is polyethylene glycol? || PEGylation Explained By Dr. Hong’s Pharmacy Classroom