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Cyclosporine Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses

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Cyclosporine is an important medication to know because you will be tested on it and you may give it depending on what type of floor you work on if you work in an icu or especially like a transplant for floor or a hospital that does a lot of transplants you’re going to be giving this medication the trade name of this medication is sand immune so cyclists born or

Sand immune you’ve probably already seen it you’ve probably seen it in some questions and let’s talk about so what it does is it prevents the rejection of transplantation it’s given for treatment of severe rheumatoid arthritis and it can also be given for management of ulcerative colitis okay so that kind has a broad spectrum of action but mostly what you’re going

To see it given for and what you’re going to be tested over with it is the prevention of rejection in transplantation so a patient comes out of can you transplant they’re going to be started on cyclosporine and the way it kind of works so what it does is it inhibits the normal immune response basically and primarily by decreasing the activity of t-cells and their

Response t-cells are a type of lymphocyte or white blood cell which play a role in cell mediated immunity so really what it does it just decreases the effect of these t-cells and their response thereby decreasing the immune response therapeutic class is immunosuppressant and antirheumatic pharmacologic classes cyclic polypeptide all right there’s a couple things

To really keep in mind here first of all we talked previously about corticosteroids and things like that but what can happen if you give this with a cortical steroid is that it increases immune suppression so in patients who have autoimmune disorders you really need to be very careful in these patients especially if there are already receiving corticosteroids

And then you throw this on top of it they’re gonna have a very decreased immune response it can cause seizures tremors hypertension hepatic toxicity diarrhea nausea vomiting and gingival hyperplasia okay so a lot of things to really keep in mind here big ones again seizures and tremors hypertension avoid with grapefruit juice while taking these medications so one

Thing that you really want to keep in mind a lot of patients once they start once they become ill once they start taking multiple medications we talk about this all the time they really kind of need to stop drinking produce okay we’re gonna be assessing our patient for any sort of signs of organ rejection and just really keeping an eye on that of course that’s why

We’re giving this medication so we want to be very careful one thing you need to educate your patient prior to going in for transplantation is you need to really educate them that this is going to require lifelong therapy for transplant patients okay it’s not something that they they have their transplant they come home they take the medication for a couple weeks

And then they’re done they’re gonna be taking this for the rest of their life again remember it can cause hypertension so you want to educate your patient on how to take their blood pressure again i just want to stress the importance of monitoring immune function and just really letting your patient know that they need to report any signs of infection and that

They’re gonna have to be treated very specially because of the fact that they are taking this and immune and then possibly also taking other corticosteroids alright so that is cyclosporine this has been another episode of the med master podcast by nrs ng keep the learning going head over to med master course calm and use the coupon code podcast met master course

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Cyclosporine Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses By NURSINGcom