Skip to content

Dapagliflozin and cardiovascular outcomes in type 2 diabetes

  • by

The pitocin and cardiovascular outcomes in type 2 diabetes definition the debacle fasil effect on cardiovascular events from bosses and mccardle infraction 58 trial evaluate the efforts of deadly force in on cardiovascular and renal outcomes in a broad population of patient who had our world at risk for adverse florid cardiovascular disease hi this is tom from

Said finals comm in this video i’m going to be explaining how sglt2 inhibitors work but sglt2 inhibitors are used in type 2 diabetes to help to reduce the blood sugar levels they differ slightly from most anti-diabetic drugs which work by either increasing the insulin in the body or increasing the insulin sensitivity of the cells of the body and the objective

Of increasing the insulin or the insulin sensitivity is to get the body to take more glucose out of the blood and to store it in the tissues and that’s how they reduce blood sugar levels however in sglt2 inhibitors they work slightly differently they work by causing the kidneys to excrete glucose into the urine and by excreting glucose into the urine you reduce

The amount of glucose or sugar that’s in the blood and the rest of the body application in nursing the cardiovascular safety profile of the paleocene a selective inhibitor of sodium-glucose cotransport to dead promoters glucose arena in patients with type 2 diabetes is undef init medication used to treat type 2 diabetes it is a single product containing two

Different medications kanaka loop sin and metformin canna callosum belongs to a group of drugs called sodium glucose code transporter two inhibitors otherwise known as sglt2 sglt2 inhibitors work by allowing the kidneys to get rid of more sugar by dumping in the urine metformin belongs to a group of drugs called big one ides big one is work by reducing the amount

Of sugar produced by the liver together these medications work to lower blood sugars this medication comes in a tablet form and is usually taken twice a day with food common side effects of this medication may include diarrhea bloating frequent urination and thirst pros and cons pros sdlt innovators block the asset lt to retain involvement in 90% of the glucose rep

Serving in the proximal honolulu resulting in increased adrenaline cole’s expression and lower blood glucose level count calories loss on body weight raise up epic insomnia as multi progressive and blood pressure urinary tract or genital infections is applied in ecuador the vast majority of patient worldwide which make the result difficult to generalize to

Black and hispanic patient the patient who were enrolled in this trial were specifically at very high cardiovascular risk we only have the patient myocardial infraction krong i actually dc previous stroke and peripheral vascular dc denies is show what that 39 patient will night to build credit for triggers provide a benefit in these outcomes so the heart failure

Community is delighted to see the results of data hf g lp two inhibitors had an impact on the incidence of heart failure and the development of heart failure but dapa hf said in patients with establish heart failure dapa actually i can’t say the whole lowered dapa actually conclusion impression with type 2 diabetes who had a word address for a tres colores

Cardiovascular disease freedman with death but gleason did not result of higher elaborate of maze from possible but did result in a lower world of cardiovascular death or hospital ation for her salary and finding that reflects a lower rate of hospitalization for her fillery with increasing problems failure of the pancreatic beta-cells superimposed on top of it our

Current treatments are largely concerned with trying to stimulate insulin secretion and improve insulin sensitivity we can’t always succeed with these agents and indeed nearly half of the patients we have at the current time don’t achieve the hpa 1 targets we’re looking for

Transcribed from video
Dapagliflozin and cardiovascular outcomes in type 2 diabetes By Damara Moncada