Diazepam is a benzodiazepine that has been around for decades. It has few safety concerns at normal doses, but does have some safety concerns, especially with higher doses. It’s used for many of the same medical reasons as other benzodiazepines and recreational use also occurs.
Diazepam is one of the oldest and most commercially successful benzodiazepines it’s been used for a long list of medical conditions including seizures anxiety alcohol withdrawal and insomnia outside of medical settings recreational use also occurs with the substance among the positive effects of diazepam a muscle relaxation sedation anxiety reduction and disinhibition
The negative effects can include dizziness motor control impairment respiratory depression confusion and memory impairment most of the recreational effects of the drug lasts for about eight hours though the effects can extend to 12 hours or more it normally begins working in 30 to 90 minutes with an onset of 60 minutes being common like other benzodiazepines the
Core structure of diazepam includes a benzene ring attached to add a zapping ring diazepam doesn’t affect the amount of gap in the brain but it effectively changes what gaba is able to do it functions as a positive allosteric modulator that means it increases gavvers effect at gaba-a receptors instead of functioning as an agonist multiple active metabolites of
Diazepam have been identified including nord as a pam temazepam and ox as a pam diazepam was the second benzodiazepine to enter the market dr. leo sternbach invented librium the first benzodiazepine and went on to develop diazepam which was released in 1963 for a couple decades after its release diazepam was the top pharmaceutical in the us and it remains widely
Used to this day when used orally a common dose of diazepam is 10 to 20 milligrams and a strong dose would be over 25 milligrams on the international level that as a pam is a schedule for drug just as it is in the united states in most countries the drug is either a controlled or prescription only substance the safety profile of diazepam is similar to that of
Other benzodiazepines but it tends to be a bit less dangerous it’s certainly possible to die from an overdose of the drug but nearly every diazepam related death involves another factor such as a second drug due to its possible safety issues at higher doses and its ability to be negatively synergistic it should not be combined with other cns depressants with the
Diazepam overdose there are some issues with the functioning of your cardiovascular in respiratory systems medical attention is recommended but even significant overdoses aren’t usually fatal anterograde amnesia also known as a blackout is a real concern of diazepam and it can occur with normal recreational doses both tolerance and withdrawal exist with diazepam
At least some tolerance usually begins forming in about a week withdrawal from the drug can be dangerous and even deadly so you must approach it carefully diazepam is a popular benzodiazepine that has been around for decades in most places it is a controlled drug or at least a prescription only substance it has a fairly good safety profile with normal doses but
There are safety concerns once you get into the higher doses any form of long-term regular use of diazepam isn’t recommended because tolerance quickly forms and withdrawal from the drug can be dangerous if you have any questions about diazepam feel free to leave them in the comment section you can also leave them in the reddit thread for this video which will be
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Transcribed from video
Diazepam (Valium): What You Need To Know By The Drug Classroom