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Digoxin Pharmacology Video

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Welcome today class you have the wonderful opportunity to sit in on a virtual patient education our patient franny and her dad rigoberto are with us today and they are going to learn about their new prescription franny is justin started on to joslyn how are you guys doing today so as you know you have been started on digoxin the trade name is lanoxin digoxin is cardiac

Glycoside an atrophic agent some other examples of this drug include amra nam dobutamine dopamine amira known entropion and miller milrinone the therapeutic classification of digoxin is that as a cardiovascular agent digoxin has a couple of different uses it is used to treat congestive heart failure usually in combination with a diuretic in an angiotensin-converting

Enzyme inhibitors is also used to treat heart rhythm problems called atrial fibrillation lastly it can be used to improve and strengthen asst efficiency of your heart or to control the rate and rhythm of the heart beat which leads to better blood circulation and reduce swelling of the hands and ankles and patients with heart problems you will be taking this

Medication for your atrial fibrillation do you have any questions so far to jackson inhibit sodium-potassium appa which increases intracellular sodium concentration leading to increased intracellular calcium concentration autonomic effects of this includes vagal momentum mimetic action umbro receptor sensitization which lead to positive inotropic action reduce

Sympathetic response and decrease renin-angiotensin system output or neural hormonal deactivation digoxin will decrease your heart rate so that the atrioventricular node which controls the electricity in your heart will increase your cardiac output cardiac output consists of your heart rate and your stroke volume so when you increase cardiac output you increase

The amount of blood those flowing through your body digoxin also causes positive inotropic effect meaning it increases the strength of the muscular contraction of your heart the ventricular rate of your heart will decrease and your facial vagal tone in your heart will be enhanced in other words the ventricle of your heart will not pump as fast as the vagal tone of

Your heart will be better you are so welcome our java’s nurse’s is to make sure you understand everything and we want to work with you to give you the best care possible next we are going to go over dosing with you usual dosing is based on various factors that include body weight age renal function and other medications taken you were given a loading dose during

Your stay years and now you’ll get amazing stokes usual doses includes 0.125 to 0.25 milligrams iv or 0.75 to 1.5 milligram by mouth you will be getting a by mouth dosage are you pregnant or is there any risk of you being pregnant okay great the pregnancy category of the strongest eve which means either studies and animals have revealed adverse effect on the fetus

Teratogenic or embryo title or other and there are no controlled studies and women or studies and women and animals are not available drugs should be given only if the potential benefit justifies the potential risk to the fetus well when you take your medication it is best to take this medicine on an empty stomach if the medicine upset your stomach you may take

It with food or milk and take the medicine at the same time each day depending on what it’s easier for you take it in the morning or at night it may be better to take it in the morning right when you wake up so you don’t have to worry about it for the rest of the day you can keep it by your bed and just take it right when you get up also be sure to take your folds

Before you take your medication you can palpate your radial pulse following the line of your song yes perfect if your pulse is below 60 or above 100 contact your doctor before you take the medication perfect there are some contraindications you will need to be aware of if you have a hypersensitivity to digoxin or other digitalis preparations ventricular fibrillation

Or renal our liver impairment you should take caution when taking this medication you should also contact your doctor before taking the medication if any of those things are a problem now there are some side effects you will have to be aware of you may have some nausea and vomiting after taking this medication and if that happens you can take the medication with

Milk or a big glass of water you may also become dizzy or get a headache or become fatigued digoxin may also cause anxiety or depressive symptoms more serious side effects for cardiac dysrhythmia ischemia sinnoh a trio block sinus bradycardia and basil constriction watch for abnormal heartbeats and paleness of extremities look for signs of strongbow cider keenya

Which is low platelet count which includes easy bruising red spots on the lower legs prolonged bleeding from cuts bleeding from nose or dung and blood and urine horse tools we will send home some information with you that will have all of these things sucky we are talking about liz’s jeter interact it looks kind of like this there are some things that the jackson

Interact with that can increase or decrease the effects of the medication drugs that increase the effects of the jackson include adrenergic agents like epinephrine ephedrine sulfate and i super oh aunt ida’s resnick’s which include am i amiodarone hydrochloride propafenone hydrochloride and quinidine calcium preparations and cast calcium channel blockers like

Diltiazem hydrochloride fellow typing nifedipine and verra verra panel drugs would decrease the effects of digoxin include antacids cholestyramine cola stifle hydrochloride or alexis and aminoglycosides herbal remedies including ginseng hawthorn licorice psyllium and st. john’s wort will also cause interactions with digestion if digoxin happens to accumulate or

If the serum level of digoxin the blood becomes too high you can get you jackson toxicity signs and symptoms of digoxin toxicity includes anorexia diarrhea nausea and vomiting headache now is blurred vision greenish halos seen around objects and confusion if this happens stop taking it neatly and call your doctor the antidote for jackson is digoxin immune fest

But is only for serious toxicity do you have any questions there are some nesting considerations that we need to tell you as well make sure to report any signs and symptoms of toxicity your doctor may want to monitor your share of digoxin levels which requires some blood work so she removes a reputed level is 0.5 to two nanograms per milliliter you may also need a

Base flied to jackson level make sure to be aware of serum electrolytes when necessary the doctor will also order blood work to that as well renal and liver function are very important when taking any medication if you notice decreased renal function or liver function make sure to contact your provider because you make it digestion toxicity if they aren’t working

Well monitor adverse effects especially for patients of hypokalemia hypomagnesemia hypercalcemia hypoxia ischemic heart disease hypothyroidism advanced age small body mass female gender and a declining renal function great well if there are no questions from you guys we will go back to the student well class thank you for joining us on our patient education of

Josten we hope you had a great time and learn just as much as our patients did thank you

Transcribed from video
Digoxin Pharmacology Video By Jasmine Serrano