Eating Disorder News Network – February 2010
Oh hello i’m dr. jeffrey dis our bow and welcome to the february 2010 edition of the eating disorder news network many treatment providers have often held that target weights are too arbitrary of a means of measure when it comes to determining a return to physical health and patients with anorexia nervosa target weights often lack reliability and validity as well
The department of radiology is st. george’s health care trust in the uk perform pelvic ultrasound on 72 female adolescents with anorexia nervosa and compared published parameters of pelvic maturity to recorded weight for height ratios and bmi of patients with anorexia researchers found that there was a wide variation in weight for height ratios and bm is at each
Grade of pelvic maturity supporting the notion that the primary arbitrary targets for weight and bmi are likely to be too high in some patients and too low in others based on this finding researchers suggests that target weight gain would be better based upon baseline pelvic ultrasound and follow-up screenings than on published charts to further understand why eating
Disorders are associated with abnormalities of body image perception researchers at the hiroshima university health center in japan investigated the functional abnormalities in brain systems during the mental processing of negative words concerning body images and patients with eating disorders brain responses to negative words concerning body images and neutral
Words were measured using functional mri and 36 patients with eating disorders and with 12 control subjects participants were instructed to select what they felt was the most negative word from negative body image word sets to select the most neutral word from each neutral word set compared to the neutral word set tasks patients with both types of anorexia nervosa
Restricting and binge purge type showed greater activation of the right amygdala while patients with binging behaviors both the bulimia group and the binge purge anorexia group had significant activation of the left medial prefrontal cortex it is suggested that these brains activations may be associated with abnormalities of body image perception as activation of
The amygdala may be involved in the fearful emotional processing of negative words concerning body image and strong fears of gaining weight while reacher’s po researchers pose one possible interpretation of the finding of the media prefrontal cortex activation being that but it may reflect an attempt to regulate the emotional response invoked by word stimuli an
Interesting case report out of istanbul turkey reports on a case of a patient with anorexia nervosa who failed treatment with conventional approaches including psychotherapy and pharmacotherapy but showed recovery after having anti-reflux surgery due to esophagogastric complications as a chronic disorder anorexia can overlap with esophageal sphincter set failure
And delayed gastric emptying which results in patients with eating disorders having a higher incidence of gastrointestinal complaints including conditions such as gastroesophageal reflux disease or gerd the overlapping symptoms of these disorders may cause problems and differential diagnosis and treatment decisions the researchers remind us that when dealing with
Patients with symptoms of eating disorders physicians should keep in mind that these patients may have serial esophagogastric complications that can affect the response to psychiatric treatment alternatively some patients with primary esophageal disorders may present with symptoms that can mimic eating disorders australian researchers examine the features of women
With bulimic type eating disorders attending primary care settings and two smaller urban regions of the united states among the findings was that although two-thirds of participants recognized the problem with their eating patterns less than forty percent had ever sought treatment from a health professional for an eating or weight problem and only one in ten had
Sought treatment from a mental health specialist additionally only one-third had ever been asked about problems with eating by a primary care practitioner or other health professional however more than eighty percent had sought treatment from the health professional for symptoms of anxiety or depression most reported some degree of discomfort in discussing eating
Problems with others and half reported that they would not be truthful about such problems if they were asked having an eating disorder was associated with several chronic medical conditions including joint pain gastrointestinal problems and fatigue although larger studies are needed for confirmation the findings suggests that the health burden of the bulimic type
Eating disorder stantial but remains largely hidden studying the general psychological medicine points the frontal lobe when looking at executive functioning in patients with body dysmorphic disorder or bdd with only a few studies of neuropsychological functioning having been deducted some previous studies have indicated executive dysfunction in bdd this study
Sought to further define these executive deficits using 14 patients meeting dsm four criteria for bdd compared to 14 age and sex-matched control participants all participants completed executive function tests including spatial span spatial working memory the stockings of cambridge tasks the pattern recognition test and a test of visual memory the results of the
Study indicate that patients with bdd have executive functioning deficits including making more errors and slower thinking times in an online manipulation planning and organization of information however spatial memory capacity motor speed a visual memory were intact research associate these findings with dysfunction in the frontal lobes of the brain a group of
Italian researchers looked at the efficacy of zonisamide an anti-seizure medication that also promotes weight loss in clinical practice anissa might has also been used off-label for management of binge eating disorder since case reports and small studies have shown potential for reducing binge eating behaviors and controlling weight gain associated with these
Behaviors researchers evaluated the efficacy and safety of zonisamide as augmentation to individual cognitive behavioural therapy or cbt and the treatment of binge eating disorder patients 24 patients were enrolled in the cbt treatment group and 28 patients and the cbt group plus zonisamide group measurements were taken at the beginning of treatment at the end of
Treatment and one year after the end of treatment patient p.m. eyes were measured and the eating disorder examination questionnaire binge eating scale back depression inventory and state trait anxiety inventory were administered results of this study showed that at the end of treatment the cbt therapy plus anacin like group had a higher mean reduction of body
Mass index with improvement on the eating disorder examination questionnaire beck depression inventory and binge eating scale scores follow up at one year further show that the cbt group regained wait while the cbt group plus zonisamide group reduce their body mass and showed even higher reduction in binge eating frequency and on the binge eating scale eating
Disorder examination questionnaire and state and trait anxiety inventory scores and finally out of massachusetts general hospital in harvard medical school and published in the journal endocrinology development there’s a report on interaction universe and the characteristic alterations of multiple neuroendocrine axes and peptides that signal or regulate energy
Intake nutritional deficiencies and imbalances result in several changes to hormones these alterations include a state of hypogonadotropic hypogonadism are nutritionally acquired resistance to growth hormone with low igf-1 levels relative hypercholesterolaemia thyroid hormone levels that commonly show low total t3 despite normal tsh low levels of leptin and insulin
And elevated levels of ghrelin peptide yy and possibly adiponectin although many of these changes are adapted to low weight they can impact bone metabolism body composition reproductive function and stature growth can also be affected low bone mass is characteristic of anorexia and both adolescent boys and girls however some unique gender differences are noted in
Girls sites of jake uhler bone which is a spongy network of cells in the interior spaces of bone are more likely to be affected than sites of cortical bone the hard late outer layer of bone whereas in boys with anorexia sites of cortical bone are more commonly affected important predictors of low bone density include nutritional factors body composition hypogonadism
Low igf-1 levels elevated cortisol and peptide yy levels with possible contributions due to low insulin and as reported in the article weight gain is see it with stabilization of bone density although residual deficits persists in the short term and in some cases long term check in next month for more updates in the field and for more information on the reports
Mentioned today see our references at the end of this newscast i’m dr. geoffrey de sorrow for the eating disorder news network wishing you a happy and healthy day you
Transcribed from video
Eating Disorder News Updates – February 2010 By EatingDisorderNews