A short video about how to calculate a metoclopramide CRI for veterinary practices.
Hey everyone my name is elias and i’m a small animal veterinarian over in england i wanted to talk to you about how to calculate and metoclopramide cri you can either run miss compromised in a syringe driver or a de anza where a patient sort of maintenance fluids for this example we will pick the the fluid bag rather than the syringe driver just to switch things up
A bit so for our example today our patient weighs 10 kilos the dose we’re going to be giving is 1.5 mix batik the day the dose range is 1 to 2 meg speak so we’re not going to commit we’re going to go right in the middle so our 10 kilogram patients needs one point five milligrams per kilogram per day when we do this our kilograms will cancel out leaving us with 15
Milligrams per day not overly helpful so we need to convert this to milligrams per hour and we know that there in one day there are 24 hours so our date is gonna cross out and that’s going to leave us with approximately zero point six three milligrams per hour so our little friend here is going to need a point six three milligrams per hour of metz compromise there’s
A couple of different ways you can go here i think what we’ll do is we’ll nail figure out how many middles per hour our patient needs so the concentration that generally is on the shelf is five mick’s per mil but always double-check before you do this so to get our mils we’re gonna divide by concentration of five milligrams per mil and that’s going to leave us with
Zero point one three mils per hour of metoclopramide so we’re going to step away from the medical by for a moment and we’re gonna look at our fluid rate so our patient weighs ten kilos and we’re giving fluids at three mils per kilo per hour which as you will figured out is equal to 30 mils per hour if we’ve got a 500 mil bag and we’re running at 30 mils per hour
Bells are gonna cancel out and that’s gonna leave us with about sixteen point seven hours worth of fluids so if we know that we’re giving zero point one three mils per hour of mists club remains and we know that this bag lasts for sixteen point seven hours we need to give sixteen point seven hours worth of medical permit so if we do sixteen point seven times zero
Point one three that’s gonna give us two point one mils of metoclopramide i have taken some liberties with rounding so i think it comes out to two point one seven if you round up at the point one three either way around 2.1 mils and then you’re just gonna add that to your bag and make sure you you mix it up thoroughly and then start running if you want to titrate
The dose in this situation then what you need to do let’s take your desired dose so let’s say you want to go up to two milligrams per kilogram per day divide it by the current dose one point five milligrams per kilogram per day and then multiply that by your current rate which is thirty which gives us 40 mils per hour if you want to go the other way you just do
The same thing your your desired dose maybe you want to go down to one so you do 1 divided by 1.5 times 30 and that will give you 20 so it’s it’s fairly straightforward to titrate up or down
Transcribed from video
How to calculate a metoclopramide CRI By Veterinary Emergency and Critical Care Education