A nonsteroidal, selective aromatase inhibitor (antiestrogen).
Letrazole letrazole a non-steroidal selective aromatase inhibitor anti-estrogen side effects generally symptoms of high pestrogenism sweating hot flashes arthralgia joint pain fatigue long-term use may lead to osteoporosis therefore for post-menopausal women are patients with osteoporosis bisphosphonates eg resedrinate allendronate ibandronate may also be
Prescribed bisphosphonates are a class of drugs that prevent the loss of bone density indications hormone-dependent breast cancer infertility caused by an ovulation medical abortion gynecomastia non-obstructive azoaspermia short stature in children growth disorder endometriosis hormone-dependent breast cancer it works by blocking estrogen production leading to
Increases in follicle stimulating hormone fsh release that can slow or stop the growth of hormone-dependent breast cancer cells that need estrogen to grow it is effective only in postmenopausal women in whom estrogen is produced predominantly in peripheral tissues i.e adipose tissue like that of the breast and a number of sites in the brain although it reduced
The recurrence of the cancer it did not change survival rate compared to tamoxifen it is ineffective in pre-menopausal women because the main source of estrogen is from the ovaries not the peripheral tissues and it is contraindicated in premenopausal women during pregnancy and lactation infertility caused by an ovulation it is also used for fertility because
It induces ovulation in women with polycystic ovary syndrome pcos or problems with ovulation because it has fewer side effects than clomiphene and less chance of multiple gestation comparisons for ovulation induction it results in significantly higher rate of locomotor and cardiac abnormalities compared to natural conception clomiphene results in significantly
Higher congenital cardiac anomalies prediction for miscarriage in the first trimester low serum levels of human chorionic gonadotropin beta hcg or progesterone combing estradiol at five to six weeks of gestation better predictors low serum levels dual of estradiol and progesterone or estradiol alone at seven minus nine weeks of gestation medical abortion for the
Anti-estrogen action it is used for medical abortion to terminate pregnancy in combination with misoprostol mephapristone is also used to cause an abortion up to week 10 of pregnancy by blocking progesterone anti-progestogen but it is expensive gynecomastia an increase in the amount of breast gland tissue in men triggered by a decrease in the amount of testosterone
Compared with estrogen the decrease can be caused by conditions that block the effects of testosterone reduce testosterone level or increase estrogen level it is most effective in the early stage such as anabolic steroids non-obstructive azoaspermia no sperm in the ejaculate due to failure of spermatogenesis in men the most severe form of male infertility the
Etiology is either intrinsic testicular impairment or inadequate gonadotropin production it promotes spermatogenesis because it improves sperm concentration and increases testosterone estradiol ratio for men with oligozoospermia who have normal testosterone estradiol ratio it is a relatively well tolerated with no serious adverse effects testicular extraction of
Sperm under an operating microscope micro tees has been the first line treatment short stature in children during childhood the growth plate matures its total width decreases and eventually it disappears at the end of puberty with complete replacement by bone along with cessation of longitudinal growth in specific disorders timing of epiphyseal fusion as advanced
Are delayed for example in patients with estrogen deficiency it is delayed and in patients with precocious puberty too soon puberty it is advanced it can be used in combination with growth hormone to delay the fusing of the growth plates it is better than testosterone with regards to improvement in testicular volume and delaying bone age progression endometriosis
A disease of the female reproductive system in which cells similar to those in the endometrium grow outside the uterus most often this is on the ovaries fallopian tubes and tissue around the uterus and ovaries some symptoms include pelvic pain heavy periods pain with bowel movements and infertility one of the cause is a high estrogen level you
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letrozole By Air to air