Group Calcium, Pharmacology 2 Video assignment- project 7. Jessica Sekulich, Shae de Waal, Alan Shakir & Jessica Monaghan.
Hi i’m destitute and welcome to another way you talk into the life of the young five whole adventure and cat toc psychiatrist dr. sherry and get on today with the latest bipolar threat he’ll then the food is that you i’ve been diagnosed with bipolar disorder and i guess it makes sense because yeah it’s just very debilitating sometimes so your sunday’s you’re gonna
Run around you buy things you learn it needs when george adults of shopping sprees and then holidays you just so depressed that he knows do reason eleanii change a lot and i don’t know what to do any doctor to wall is a psychiatrist who is currently researching the latest bipolar treatments so can you briefly describe crosswalk white collar involves survived father
Is a movie or affective disorder characterized by extreme in a patient’s personality whichever elevated or many faiths and the depressive phase but it can be further categorized into two groups bipolar one which is defined as one or a lifetime episodes of mania and usually attacks of depression and bipolar 2 for hydro mania and depression but norman what drugs are
Currently approved for the use of treatment of bipolar larass put ip and olanzapine paroxetine while the drugs currently approved by the fda and the treatment of bipolar depression and how do these drugs work in relieving the symptoms of bipolar the newest drug on the market for the treatment of bipolar disorder is loratadine its mechanisms that can ism of action isn’t
Entirely known but it is thought that the drug is a dopamine d2 and serotonin 5-ht 2a receptor antagonist it also has moderate antagonistic activity on the alpha to see and to a adrenergic receptors the classical atypical antipsychotic described for bipolar disorder is quetiapine quetiapine has significant antidepressant activity in the depressive stage of bipolar
Disorder it has antagonistic action on the 5-ht 1a 5ht to d1 d2 histamine 1 and alpha 1 and 2 receptor sites in the brain allowed to be fluoxetine combines an atypical antipsychotic with a selective serotonin reuptake inhibitor to restore neurotransmitter balance in the brain particularly levels of serotonin dopamine and norepinephrine the antipsychotic effects of
Olanzapine a due to its antagonist action on the serotonin 5-ht 2a and dopamine d2 receptor sites are luring excited which has side effects right now gastritis the side effects of the lens diarrhea right now and increased weight gain so it seems each drug has their own respective side effects with this in mind what are the advantages of one drug open data and
Which do you believe is the most beneficial drug on the market based on current research lurasidone has been found to be the most advantageous of the three drugs this is because it has fewer side effects than conventional antipsychotics and also lower drug to drug interactions and therefore it can be used as an adjunct therapy quetiapine has fewer extrapyramidal
Side effects so it may be useful for patients who are displaying parkinsonian like symptoms from other drugs it is also effective against both the positive and the negative symptoms of bipolar disorder whereas the other drugs are more effective against the depressive symptoms olanzapine paroxetine combination therapy is associated with fewer extrapyramidal side
Effects it also has been found to have better efficacy against the depressive symptoms of bipolar disorder as opposed to monotherapy antipsychotics consideration does have to be taken into account regarding the weight gain that can be associated with olanzapine paroxetine therapy overall laura thoren is the first line treatment in most situations as it does have
Fewer side effects and drug to drug interactions
Transcribed from video
mental health plus – Bipolar treatment, version 2 By UTS Pharmacology