Skip to content

Methotrexate Mnemonic for Nursing Pharmacology (NCLEX)

  • by

Study this Methotrexate NCLEX mnemonic and other mnemonics with Pixorize.

Methotrexate is a medication used to treat cancer as well as some autoimmune diseases like rheumatoid arthritis in this mnemonic video i’ll teach you an easy way to remember everything you need to know about methotrexate let’s get started for today’s video we’re hopping on the filming set for the movie the matrix you know the movie with keanu reeves about an altered

Reality well the matrix can help you remember today’s drug methotrexate you know since matrix kind of sounds like methotrexate let’s start off by talking a little bit about how methotrexate works this take of the movie is not going as planned and the movie director has just about had it in his frustration he is ripping the folder with the script in half here at

Pixarize we use a folder to represent folate in this case the folder here is being ripped because methotrexate works as an anti-folate or a folate antagonist by blocking folic acid signaling methotrexate is able to stop dna replication and therefore stop cell division why would that be useful well let’s talk about that next in front of him the movie director has

Catered a plate of yummy buttery crab you know since movie directors are rich and famous they are always eating high-end food here at pixarize we use a crab to symbolize cancer just like the zodiac sign for cancer is a crab methotrexate is a form of chemotherapy that is useful in stopping the rapid cell division that occurs with cancer but it actually does more

Than just treat cancer so let’s talk about that next the matrix has this famous scene of keanu reeves bending over backwards to dodge bullets remember on the set the bullets are exploding behind keanu and a film crew member is containing the flames of the explosion with a fire extinguisher a fire extinguisher is our recurring symbol for anti-inflammatory agents

Just like a fire extinguisher puts out inflammatory flames methotrexate puts out inflammation because of its anti-inflammatory properties methotrexate is also used to treat some autoimmune diseases that cause inflammation you actually need to know just the most important disease for the nclex here so we’ll cover that next as keanu reeves was leaning way back for

His stunt he got distracted and lost his balance the way he is banging his knee and elbow hard on the floor reminds me of the autoimmune disease rheumatoid arthritis because rheumatoid arthritis causes inflammation in your joints like your knees and elbows like i mentioned before the anti-inflammatory properties of methotrexate are used to reduce inflammation and

Treat rheumatoid arthritis next let’s talk about some potential side effects of methotrexate the movie director is the one who puts the scene in action see that lever next to him well when the director pulls that lever the bullets shoot in the pixerized universe we use a lever as our symbol for the liver because liver and lever sound alike right plus the handle

Of this lever even looks like a liver don’t you think this is here to help you remember that methotrexate can cause liver damage also called hepatotoxicity the nurse will be responsible for monitoring the patient’s liver enzymes the patient should also be instructed to avoid alcohol and any other substances that harm the liver to prevent further damage as the

Director pulled the lever he bumped the table with his catered food in addition to the crab which we already talked about there is a pile of empty hollow bones the director already ate the bone marrow out of these bones and due to the bump they are now falling to the floor these hollow empty falling bones are here to help you remember that methotrexate causes

Bone marrow suppression a common side effect of chemotherapy the bone marrow is responsible for creating blood cells like red blood cells white blood cells and platelets so bone marrow suppression leads to anemia causing power and fatigue by reducing red blood cells and increased risk of infection by reducing white blood cells and a higher risk of bleeding by

Reducing platelet count we’re getting closer to finding out what made keanu reeves lose his balance in the first place something was making him super nauseous the way his face is green like that makes me think he’s about to vomit when you think of this movie actor feeling nauseous remember that methotrexate can cause gi disturbances like nausea vomiting diarrhea

And loss of appetite methotrexate is also known to cause stomatitis which refers to ulcers or canker sores forming inside the mouth these gastrointestinal side effects may be treated with folic acid supplementation if you remember earlier we talked about how methotrexate is a folate antagonist meaning that the drug works by blocking folate in the body so giving

Folic acid actually slightly reverses the effects of methotrexate including the nasty side effects however taking too much folate can make the drug completely ineffective because of this patients should only take folic acid supplements after consulting with their provider aha the culprit of this whole fiasco is a tarantula crawling across the movie set keanu reeves

Was disgusted by the creepy crawly guy causing him to get nauseous and lose his balance which in turn made the director angry and rip his folder see how it all came together by the way this tarantula is our symbol for teratogens it’s the teratogenic tarantula methotrexate is a teratogen that can cause birth defects like spina bifida in the fetus and should not be

Given to pregnant women even after discontinuing the drug it’s advised that patients do not become pregnant for at least three months if a patient taking methotrexate is found to be pregnant the provider should be notified immediately the patient will usually be given a high dose of folate supplementation to reverse the drug’s effects as much as possible alright

Now that we’ve covered everything you need to know about methotrexate let’s summarize methotrexate is a medication that works by blocking or inhibiting folate this blocks cell division which can be used to kill rapidly divided cells like cancer cells due to this methotrexate is often used as a chemotherapy to treat various forms of cancer it is also used for its

Anti-inflammatory effects to treat autoimmune diseases like rheumatoid arthritis side effects of methotrexate include hepatotoxicity bone marrow suppression and gastrointestinal disturbances including stomatitis folic acid supplementation may help alleviate severe gi side effects but remind patients to consult with their doctor beforehand finally methotrexate

Is teratogenic and should not be taken by pregnant women we better let these guys get back to filming thanks for joining me on the matrix movie set until next time thanks for watching for more videos like this one subscribe to our channel and check out our newest lessons for more resources on this topic including fact lists and interactive review images click the

Image next to the more here arrow i’ll see you next time

Transcribed from video
Methotrexate Mnemonic for Nursing Pharmacology (NCLEX) By Pixorize