In this episode, I discuss a medication known as nabumetone (Relafen).
Hey everybody welcome back to drug talk as always i’m your host gary campbell in today’s video we’re going to be discussing the medication known as nabumatone it’s brand name is relefin and before i talk about the medication itself just keep in mind that this channel is for information purposes only and not to be used as a source for recommendations for your
Personal health care now during this presentation we’ll discuss the mechanism of action or how this medication works indications or reasons we prescribe this medication to a patient followed by contraindications or reasons we would not be able to prescribe nobumatone then touch on an example of dosing and finish it off with side effects with percentages i put
Together some slides to go over this information so let’s jump right into it the first thing to discuss here would be the mechanism of action or how this medication works though nabumatone is a pro-drug that is biotransformed into 6 mna and is a non-steroidal anti-inflammatory drug it also has anti-pain and anti-fever activity the anti-inflammatory property
May be attributed to its ability to inhibit prostaglandin synthesis in terms of indications or reasons we prescribe this medication to a patient we may see use in the treatment of osteoarthritis as well as in the treatment of rheumatoid arthritis with respect to contraindications or reasons we would not be able to prescribe nabumatone well we wouldn’t give this
Medication to a patient to a hypersensitivity to imbuematone or to any other component of the formulation if a patient had asthma urticaria or an allergic type reaction following aspirin or other nsaids in the past they would also not use this medication finally this medication would not be used in the setting of a cabbage or coronary artery bypass graft surgery
Now for an example of dosing with nebutone though in the treatment of osteoarthritis and rheumatoid arthritis the dosing would be the same the initial dose would be 1000 milligrams orally once a day and the maintenance dose should be one thousand to two thousand milligrams per day given orally divided one to two times as with all medications there are some side
Effects or adverse reactions that patients may experience while using the bumatone we’ll go over some of those here now some common side effects may be edema happening three to nine percent of the time paritis or itchiness of the skin again coming in at three to nine percent a rash which may happen up to nine percent of the time or abdominal pain which may happen
12 percent of the time three to nine percent of patients may experience constipation and fourteen percent may experience diarrhea in indigestion seems to happen thirteen percent of the time and nausea three to nine percent up to fifteen percent may have an increase in their liver function tests and up to nine percent may have dizziness feeling of nervousness
Comes in between one and three percent of the time and a headache at three to nine percent insomnia may happen between one and three percent of the time and one to three percent of patients may experience somnolence now some more serious side effects would be hypertension or high blood pressure bronchospasm or angioedema all right everybody that’s all we’re going
To talk about today with nabumitone or relefin as i wasn’t very thankful for the time to buy and watch on my videos if you found the information valuable you’d like to help grow this channel remember you can like the videos share the videos most importantly subscribe to the youtube channel there’s also some links in the description you can check it as well that’s it for today take care
Transcribed from video
Nabumetone (Relafen) – Pharmacist Review – Uses, Dosing, Side Effects By Drug Talk