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Osteoporosis Medications – Pharmacology – Musculoskeletal | Level Up RN

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In this video, Cathy covers medications that are used to treat osteoporosis, including: bisphosphonates (alendronate), selective estrogen receptor modulators (raloxifene), and hypocalcemic agents (calcitonin).

Key musculoskeletal medications that you should  know. and specifically in this video, we will be   covering medications used for osteoporosis. if you  are following along with your cards, i am on card   okay, so let’s talk about first medication class   which are bisphosphonates. and the key medication  alendronate can be used

For postmenopausal  osteoporosis as well as paget’s disease,   the mode of action of alendronate is to prevent   of osteoclasts. so normally, osteoclasts are   breaking down the bone and taking calcium from the  bone into the bloodstream. and we don’t want that,   right? we want that calcium to stay in the bones. 

So that’s what alendronate helps to do, right? it   prevents the osteoclasts from breaking it down,  in terms of the side effects, the key side effect  that’s going to be important for you to remember   other side effects include gi upset,  there are some key teaching points  and they are listed on this card here, card 93 in 

Bold and red. so definitely review those things.  this on an empty stomach in the morning   with a full glass of water, and then after they  take this medication, we do not want the patient   lying down because that can really result in that  esophagitis. so after they take this medication,   minutes to prevent that esophageal

Ulceration that   also we’re going to want to encourage our patient   to increase their intake of calcium and vitamin d,  because vitamin d is needed for calcium absorption   and they should also engage in weight-bearing  exercises to help preserve their bone mass. and   so my little trick for remembering this,  i think

Alen, some guy name alan drones on and on  about his esophagitis. the other little trick that   you might use to remember this is after you take  your alendronate, maybe go out and fly your drone,   you fly your drone. maybe you’re sitting   drone, right? so if you fly your drone for 30   minutes after you take alendronate,

Then that  will help prevent that esophageal ulceration.  estrogen receptor modulator which is raloxifene.   can also help reduce the risk for breast cancer. the mode of action is that it binds estrogen   in terms of the side effects, the key side   effect i would remember includes an increased risk  for embolic events. so this

Includes things like a   dvt, a pe, or a stroke. this medication does carry  a black box warning for just this reason because   of the increased risk for clots. in addition,  for teaching, you want to make sure  your patient is increasing their intake   and then we want to monitor  the patient’s bone density.  in terms

Of how i remember this medication, if you  look at the name raloxifene, and you look at it   backwards, it has fix and then the letter o. so i  think that raloxifene will fix your osteoporosis.   okay. finally, let’s talk about a hypocalcemic  agent, meaning an agent that helps to bring down   calcium levels in the blood. so the

Medication  calcitonin is used for post-menopausal  osteoporosis as well as hypercalcemia, meaning   inhibiting the activity of osteoclasts. it  in terms of the side effects, gi  taking it through the intranasal route, then  in terms of teaching, we’re going  make sure you’re getting enough calcium  and vitamin d, weight-bearing

Exercises,   in terms of how i remember this medication, if  you look at the word calcitonin, you think ‘tone   it down,’ meaning tone down that calcium. bring  those calcium levels down in the bloodstream.  so that is it for our osteoporosis medications. in  my next video, we will cover medications for gout.   get through these meds together!

Transcribed from video
Osteoporosis Medications – Pharmacology – Musculoskeletal | @Level Up RN By Level Up RN