USMLE TETRACYCLINE
Okay so let’s talk about tetracycline first of all what are the different types of tetracycline there is doxycycline dominque recyclin minocycline okay and obviously tetracycline what’s the mechanism of action of tetracycline this is one of those drugs which inhibits the 30s ribosomal subunit okay and how does it inhibit it will not allow the aminoacyl-trna from
Sitting from its 30s from visibles opinion position okay so it will prevent attachment of aminoacyl-trna sleep will even attachment of okay and some of the things we should be no knowing when we’re talking about your recyclin is that it is we should not be taking it with milk or antacid okay because it will bind to the tetracycline and we’re going to absorb it less
Because of diabete i should not be taken with diving and cations okay um anything else for mechanism of action i think i also miss that it’s iron containing compounds and antacids iron containing compounds and antacid okay all right let’s move on to the clinical use just a quick question what other drug in the in the microbe section does the same thing it will not
Allow divalent absorption that cation will will interfere with absorption it’s actually fluoroquinolone okay okay so let’s talk about the clinical use i’m sure you know the mnemonic for this when it’s vacuum the bedroom so v is for real it is for acne this one acne minocycline is used here bsc is for chlamydia face for canadian u is for your urea plasma neurolytic
Um m is for mycoplasma thank you the t is for tularemia ch is for h pylori h pylori and bedroom v is for borrelia burgdorferi also bartonella so there’s two bees here and our it’s for rickettsia virus where we can see okay so let’s quickly read one more time this phobia cholera is for acne c is for chlamydia your plasma urea litical mycoplasma tularemia h pylori
Burgdorferi bartonella and rickettsia what are some of the drugs used for h pylori other than tetracycline we can use metro we can use amoxicillin we can use proton pump inhibitor sorry about that we see these often okay so let’s talk about the toxicities okay there’s quite a few toxicities for tetracycline the results are nice new morning well it’s actually
My mnemonic so i don’t know how other people do it the way i do it is g b t p p okay gbt pp there’s quite a ride to it right g is for gi distress v is for bone bone growth problem in children t is for teeth discoloration p is for for sensitivity in the last facebook pregnancy okay that’s about it the last thing i wanted to talk about was the different types of
Tetracycline which is right here one thing we have to know that doxycycline is hepatic le excreted sorry fecal e excreted freakily literally eliminated as a result can be used in patients with renal failure so and we used with renal failure simple right the next thing is de mikvah cycling chemicals like it can also act as in 88 and tag nest what does that mean
When there is too much adh to make the cycling can be used for example it can be used in the disease siadh which is syndrome of inappropriate age so there’s that’s when the urine concentration is going to be so so so so low because urine is not concentrated okay so that’s about it and also doxycycline is used for lyme disease i know they’re all used for all these
Bugs but this one is specifically used for lyme disease so try to remember that – alright so that’s about it and please visit my blog for the notes for the tutorials if you think it’s helpful other than that i’ll see you in my next video bye for now
Transcribed from video
USMLE TETRACYCLINE By 100lyric