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In this video we’ll briefly discuss what is vitamin d3 coal calciferol vitamin d2 ergocalciferol calcidiol and calcitriol they refer to various forms of vitamin d we’ll learn what it’s used for how it works the dose and side effects contra indications and precautions vitamin d belongs to the family of fat soluble vitamins which include vitamins a d e and k these
Vitamins are absorbed well with fat and are stored in the liver and fatty tissues there are two main forms of vitamin d in the diet vitamin d2 ergocalciferol found in plant foods like mushrooms vitamin d3 coal calciferol found in the flesh of fatty fish such as salmon tuna and mackerel and fish liver oils are among the best sources small amounts of vitamin d
Are found in beef liver cheese and egg yolks also foods such as cow’s milk soy milk orange juice cereals and oatmeal are sometimes fortified with vitamin d however sunlight is the best natural source of vitamin d3 the uv rays from sunlight convert cholesterol in your skin into vitamin d3 vitamin d3 colcalciferol is synthesized in the skin from 7d hydrocholesterol
During exposure to ultraviolet light then it is transported to the liver and is converted by 25 hydroxylase in the liver to calciol also known as 25 hydroxy vitamin d and subsequently converted by one alpha hydroxylase in the kidney to the most active form 125 dehydroxy vitamin d calcitriol this process also takes place in different tissues and cells in the immune
System such as lymph nodes alveolar macrophages and also an alveoli themselves vitamin d is known to play an important role in bone metabolism through regulation of calcium and phosphate homeostasis and may also play an important role in immune system regulation it promotes the absorption of calcium in the gut and retention at the kidneys this increases serum
Calcium levels and decreases phosphate levels parathyroid hormone and bone resorption it is available in many concentrations as vitamin d3 vitamin d2 calcitriol and alpha calcitial they are available as capsules oral solution and injection in addition to causing rickets vitamin d deficiency has been linked to respiratory infections such as pneumonia tuberculosis
And bronchiolitis pneumonia is a severe form of acute lower respiratory tract infection and is the leading cause of death in children worldwide some studies have suggested that vitamin d supplementation can decrease the frequency and severity of respiratory infections among children however further research is needed before specific recommendations can be made
So vitamin d is indicated in the prevention and treatment of vitamin d deficiencies rickets and osteomalacia the usual dose for prevention of vitamin d deficiencies when using 50 000 international units tablet or capsule for children under 5 years 100 000 international units every three months during periods of limited sunlight and for children over five years and
Adults the usual dosage is 100 000 international units every three months or 200 000 international units every six months and for pregnant women 100 000 international units around the sixth or seventh month of pregnancy and the usual dosage of vitamin d when using an oral suspension for children and adults is 400 international units once daily during periods of
Limited sunlight and for children rarely exposed to sunlight or dark-skinned children doses may be doubled and for the treatment of vitamin d deficiencies the usual dosage for children and adults is 800 to 4 000 international units once daily for six to 12 weeks then continue with preventive dose do not exceed 600 000 international units per year in general
Consuming 400 to 800 international units of vitamin d should meet the needs of 97 to 98 of healthy people vitamin d is generally well tolerated so stop treatment if signs of overdosage happen such as headache anorexia nausea vomiting increased thirst and polaria combined with a calcium supplementation at the start of curative treatment 500 milligrams to 1 gram
Per day avoid combination with thiazide diuretics do not administer to patients with hypercalcemia hypercalceria calcicolythiosis there is no contraindication during pregnancy and also not contraindicated during breastfeeding but when curative treatment is being administered to the mother do not give vitamin d to the child that’s all for this video subscribe
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Transcribed from video
Vitamin D3 (Cholecalciferol) – Vitamin D2 (Ergocalciferol) – Calcitriol: Sources, Uses, Dosage … By Medical Videos [ ANIMATED ]