Skip to content

Xigduo (dapagliflozin, metformin)

  • by

Xigduo tablets contain a combination of dapagliflozin and metformin. Dapagliflozin and metformin are oral diabetes medicines that help control blood sugar levels. Dapagliflozin works by helping the kidneys get rid of glucose from your bloodstream. Metformin lowers glucose production in the liver and also causes your intestines to absorb less glucose.

Hi welcome to our telehealth medicine information video i’m garvin and this video is on exigent duo so exege duo tablets contain a combination of dap agles flozen and metformin so dapagliflozin and metformin are oral diabetes medicines that help control blood sugar levels dap agla flows and works by helping the kidneys get rid of glucose from your bloodstream

Metformin lowers glucose production in the liver and also causes your intestines to absorb less glucose so exid duo is used for type 2 diabetes in adults aged 18 years of age and over these tablets are licensed for use in people with type 2 diabetes whose blood sugar is not controlled by the maximum tolerated dose of metformin alone or who are already taking

Metformin and dapper flossin as separate tablets exiged duo tablets can also be used for people with type 2 diabetes whose blood sugar is not sufficiently controlled by other anti-diabetic medicines it can be added to treatment with a sulfonylurea such as glycoside or glybin claymite or to treatment with insulin how does exige duo work so in type 2 diabetes

The cells in the body become resistant to the action of insulin insulin is the main hormone responsible for controlling the level of sugar or glucose in the blood it makes cells in the body remove sugar from the blood when the cells are resistant to insulin this makes blood sugar levels rise too high metformin is a anti-diabetic medicine known as a big guanide

It works in a number of ways to decrease the amount of sugar in the blood firstly it reduces the amount of sugar produced by cells in the liver secondly it increases the sensitivity of muscle cells to insulin this enables these cells to remove sugar from the blood more effectively finally it delays absorption of sugar from the intestines into the bloodstream

After eating so that there is less of a spike in blood sugar levels after meals that by glyph lawson works in the kidneys where it allows the body to excrete excess glucose from the blood into the urine normally when the kidneys filter and clean the blood glucose is filtered out of the blood at the same time the glucose is then reabsorbed back into the blood

By a mechanism called the sodium glucose co-transporter too so the kidneys normally reabsorb glucose back into the blood even when the levels of glucose in the blood are too high as in diabetes so dapagliflosin works by inhibiting this sglt2 transporter this allows excess glucose to be filtered out of the blood and excreted in the urine this will reduce blood

Sugar levels stapa act livelocan has two other effects that may be a benefit for people with diabetes firstly it may cause weight loss due to the loss of sugar from the body secondly it causes a small increase in the amount of water being filtered out of the blood into the urine this may help to reduce blood pressure so how do you take exiged jewel one exit your

Tablet should be taken twice a day with breakfast and an evening meal on a regular basis the tablet should be taken with food if you forget to take your tablet at your usual time take it with food as soon as you remember however if it is nearly time for your next dose leave out a forgotten dose do not take a double dose to make up for a mistake what should you

Know before taking exit duo tablets it is important that you continue to follow the diet and exercise advice given to you by your doctor while you take exchange due this medicine only helps control blood sugar levels and should not be used as a substitute for healthy eating and taking regular exercise so who should not take exit duo tablets so first of people

With type one diabetes people with diabetic ketoacidosis people taking the medicine pioglitazone for diabetes also not to be used with people with decreased kidney function and people with liver problems also not to be used by people who are dehydrated people with severe infections or blood poisoning women who are pregnant or breastfeeding also not to be used

With people who are allergic to an ingredient into medicine an exid duo is not recommended for people taking loop diuretics such as frucamite exiguo is not recommended for people over 75 years of age or for children and adolescents under 18 years of age because it has not been studied in these age groups exigue should be used with caution by elderly people

People taking medicines for high blood pressure who have a history of low blood pressure people with heart disease also be used for caution with people with a high percentage of red blood cells in their blood and caution in people with a history of frequent urinary tract infections and people with a history of frequent genital infections such as trash can you

Take exigue while pregnant or breastfeeding so the safety of dapaglivlosin for use during pregnancy has not been established and for this reason exiged duo should not be used during pregnancy diabetes is usually controlled using insulin during pregnancy because this provides a more stable control of blood sugar if you get pregnant while taking this medicine or

Planning a pregnancy you should seek advice from your doctor it is not known if dapaglivlosen passes into breast milk for this reason the manufacturer states that exit duo should not be used by breastfeeding mothers so get advice from your doctor if this relates to you so some of the main side effects of exiged duo so common side effects would be low blood sugar

Levels and when this is used with a sulfonyl urea such as glybin clay mite or with insulin also disturbances of the gut such as nausea vomiting diarrhea and also calmer would be a loss of appetite and vaginal trash or inflammation of the penis or foreskin due to a thrush infection and urinary tract infections and difficulty or pain passing urine increased

Production of urine and back pain dizziness increased percentage of red blood cells in the blood and changes in the levels of cholesterol and other fats in the blood and taste disturbance usually a metallic taste if you want any more information about the risks or side effects associated with exiged duo you can talk to your doctor or pharmacist to read

The patient information leaflet that comes with the medicine so can you take other medicines with exiged duo exige duo should not be used in combination with pioglitazone the pathfinder glitter zone may enhance the effect of diuretic medicines such as flusamide or bendra methioside which help to remove water from the body if you’re taking exige duo with a

Diuretic your doctor may need to change the dose of the diuretic medicine to make sure that you do not lose too much fluid there may be an increased risk of developing lactic acidosis if you take medicines that can affect your kidney function with metformin so these include diuretic medicines such as flusamide non-steroidal anti-inflammatory drugs or nsaids such

As ibuprofen or naproxen if you are prescribed any of the following medicines which exit duo you may be more likely to get low blood sugar or hypoglycemia so your doctor may want you to monitor your sugar levels more frequently if you start treatment with one of these and they are ace inhibitors such as captopril and monoamine oxidase inhibitor antidepressants

Such as phenylalazine or isocarb oxide order anti-diabetic medicines such as sulfonylureas such as glycoside or glybine claymite or insulin medicines that increase blood sugar levels as a side effect may make exit exigio less effective at controlling blood sugar medicines that can increase blood sugar levels include the following antipsychotic medicines such as

Chlorpromazine or olenazopine and rispiridon beta2 agonists such as salbutamol or salmeterol corticosteroids such as prednisolone and glucosamine estrogens and progestogens such as those found in oral contraceptives are hrt diuretics such as bender or flu methioside or frusamide arctriotide and lan rheotide may also affect sugar levels if you’ve been treated

With one of these medicines your doctor may want to check your blood sugar levels and adjust your metformin dose if necessary so the following medicines may increase the blood level of metformin which could increase the risk of side effects your doctor may need to reduce your metformin dose if you take regularly one of these so cemetidine dilute trevir real

Pyravine taylor previer topper mate and fang etinib a drop in the number of blood cells called platelets in the blood has been seen in some people taking the antihistamine keto typhoon in combination with metformin the manufacturer of keto typhoon recommends that it should be avoided in people taking metformin so that brings this video to an end if you have any

Questions you can contact us to our website or call to lynch’s pharmacy douglas cork or you can ring 43692 to find out more thank you for watching stay healthy and stay informed

Transcribed from video
Xigduo (dapagliflozin, metformin) By G. J. Lynch